Request for Information on Catalyzing the Development and Use of Novel Alternative Methods to Advance Biomedical Research 

June 22, 2023

At the recent Advisory Committee to the NIH Director (ACD), one of NIH’s newest ACD working groups looking at the issue of Novel Alternative Methods (NAMs) presented a status update.  NIH has published a request for information (RFI) to help inform the ACD working group’s deliberations.

Take Advantage of Our Many Resources for Enhancing the Rigor of Animal Research

February 10, 2023

The Advisory Committee to the NIH Director recommended ways for NIH to improve the rigor, reproducibility, and translatability of the research we support involving animal models. I updated the ACD this past June on our implementation of their recommendations. Here, in lieu of going through each of the report’s five themes, I will highlight some approaches raised during the meeting in response to their recommendations.

“All About Grants” Podcast – Alternatives to Animals

November 18, 2020

Considering alternatives to animals in your application is the topic of our next NIH All About Grants podcast. Drs. Neera Gopee with the NIH Office of Laboratory Animal Welfare and Christine Livingston with the National Center for Advancing Translational Sciences join us for this conversation (MP3 / Transcript). We will go into the 3Rs (replace, refine, and reduce), helpful resources for relevant policies, what’s needed for the vertebrate animal section, role for IACUCs and peer review, as well as organoids, in silico models, and other alternatives…oh my again!