September 20, 2023
Earlier this month, we released a Request for Information seeking public input on the humane care and use of laboratory cephalopods at Assured institutions. The proposed guidance acknowledges the evidence suggesting these animals would benefit from oversight, but also that there are not yet specific care and use standards to allow them to be regulated under the Public Health Service Policy for the Humane Care and Use of Laboratory Animals.
August 14, 2023
As NIH has been emphasizing for more than a decade, the rigor and transparency of a study are key for gleaning the robustness of its results. This includes the design, implementation, analysis, and interpretation of experiments.
March 16, 2023
Are you proposing to use key biological and/or chemical resources like cell lines, specialty chemicals, antibodies, or other biologics in your application? Learn more about authentication plans.
February 10, 2023
The Advisory Committee to the NIH Director recommended ways for NIH to improve the rigor, reproducibility, and translatability of the research we support involving animal models. I updated the ACD this past June on our implementation of their recommendations. Here, in lieu of going through each of the report’s five themes, I will highlight some approaches raised during the meeting in response to their recommendations.
July 21, 2022
NIH expects that sex as a biological variable (SABV) will be factored into research designs, analyses, and reporting in pre-clinical and clinical studies. But, how exactly do you account for SABV? Dr. Chyren Hunter with the NIH Office of Research on Women’s Health explains more in this NIH All About Grants podcast episode.
March 14, 2022
We have been busy over the past several months and are happy to announce you can now find helpful resources for stepped wedge group-or cluster-randomized trials (SWGRTs) and more than 15 other study designs and methodological issues on the RMR website.
May 10, 2021
To fully benefit from the exponentially growing body of biomedical data, we need cutting-edge approaches that foster data access, analysis, sharing, and collaboration so novel scientific questions can be pursued. But the sheer volume, sometimes siloed nature, along with the costs and time associated with analyzing large datasets, can be difficult for some researchers. Recognizing these concerns, NIH is helping by hosting large data sets and bringing together computational tools and cloud technologies in ways that support open access, interoperability, and collaborative analyses. We encourage you to explore how these resources may help accelerate your research in ways not possible before. Read on for more…
April 12, 2021
Interest in sex and gender in research—and resources to help investigators—is growing. In the 5 years since NIH enacted its pioneering Policy on Sex as a Biological Variable (SABV) (see our progress report here), there has been a lot of activity, including increased attention on sex differences and influences and many questions and requests for assistance. I’m pleased to announce the NIH Office of Research on Women’s Health (ORWH) has issued two new courses, Sex as a Biological Variable: A Primer and Bench to Bedside: Integrating Sex and Gender to Improve Human Health, to our suite of free e-learning offerings.
January 8, 2019
For your convenience, here is a roundup of recently announced changes impacting grant application submission for due dates on or after January 25, 2019.
December 13, 2018
Advancing public health depends on science being empirical, transparent, and rigorous. As yet another step towards fostering rigorous science, we have revamped the Rigor and Reproducibility webpage to highlight and include more resources you might find helpful. Since sketching out our plan last summer with the Advisory Council to the NIH Director, the webpage now reflects policy updates and explores new resources, all in a simple and easy to read manner.
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