Listening to Our Stakeholders On Considering Sex as a Biological Variable

One year ago, NIH announced a plan to adopt a new policy requiring a deliberate approach to the consideration of sex as a biological variable (SABV) in preclinical research. (Read the article, co-authored by Janine Clayton and NIH Director Francis Collins, here.) Since that moment, we have been working diligently and collaboratively inside and outside NIH to craft meaningful policy that promotes the best science. …. Continue reading

New Reporting System for Research Involving Chimpanzees

In April, NIH launched a new reporting system for requests to use chimpanzees in research, which must be reviewed by the NIH Chimpanzee Research Use Panel (CRUP).

The CRUP review process was developed following an NIH-commissioned Institute of Medicine (IOM) report on chimpanzee use in research, and recommendations from the Council of Councils, an advisory body to NIH. As described in NIH Guide Notice NOT-OD-14-024, the CRUP will review whether requests to the NIH to use chimpanzees in research are consistent with IOM principles and criteria, independent from existing NIH review processes. Continue reading

More ASSISTance Options for Submitting Your Application to NIH

I’m excited to tell you about a new option for submitting your R01 applications to NIH. Today, we made ASSIST (the Application Submission System and Interface for Submission Tracking) available as an option for submitting your R01 applications, as well as most individual career development (K) award applications. ASSIST is a web-based system that was developed by NIH, in close partnership with, to address common application submission challenges identified by the community. We first launched ASSIST …. Continue reading

Looking at Recent Data on R21 and R01-equivalent Grants

One topic of frequent interest to NIH leadership is how R01-equivalent awards compare to other research grant awards. The R01 is the standard mainstay of NIH’s research portfolio, and the oldest grant mechanism in use by NIH. As those familiar with the blog and RePORT know, we usually look at R01s in conjunction with other awards providing similar support analogous to an R01, which includes R37s or MERIT program awards. Of the R01-equivalent pool however, R01s make up the overwhelming bulk of these grants so while we call them R01-equivalents for accuracy-in-reporting reasons, it is highly appropriate to consider R01-equivalent data as representative of R01 trends. Over the past years we’ve been looking at trends in R01-equivalents compared to trends in awards through the R21 activity code. …. Continue reading