Conversations About NIH Support of Graduate Training Programs

December 2, 2015

Monday, in a blog post on the Feedback Loop, colleagues at NIGMS outline the recent history of NIH’s efforts that impact graduate student training, as well as recent discussions beyond NIH on how to modernize and revitalize graduation education and training.

These conversations raise an important question, “Is NIH’s support of graduate-level training keeping pace with how we do science?”. …..

Update on the Postdoctoral Benefit Survey

November 30, 2015

In 2014, the NIH announced that it was going to distribute the NIH postdoctoral benefits survey to collect information on benefits available to postdoctoral researchers at different institutions. The survey was launched in response to a report on the biomedical research workforce from an Advisory Committee to the Director (ACD) working group. ….

How Would You Address Diversity in the Physician-Scientist Workforce?

November 24, 2015

As part of a wider initiative to shape the future direction of research training for the biomedical workforce as a whole, we at the NIH are actively pursuing ways to examine the physician-scientist workforce and to optimize training for clinicians seeking research careers. Physician-scientists face some challenges and career transition pathways unique to being in a clinical career track, hence the need for a specific focus on this workforce.

An Opportunity to Collaborate and Use the Unique Resources of the NIH Clinical Center

November 18, 2015

Three years ago, NIH created a program to enable extramural researchers to collaborate with our intramural scientists and use the exceptional resources of the NIH Clinical Center. Since then, 20 awards have been made to support projects of significant breadth, such as a trial for treatment of relapsed leukemia; a malaria vaccine trial; and a trial testing a new cardiac catheter. This is the fourth year that NIH has issued this funding opportunity. The December 15 pre-application deadline is approaching, and I wanted to remind you what this program offers. ….

Perspectives on Peer Review at the NIH

November 12, 2015

In today’s New England Journal of Medicine, Richard Nakamura, the director of NIH’s Center for Scientific Review (CSR), and I published an essay titled “Reviewing Peer Review at the NIH.” As the competition for NIH research grants has become increasingly stiff, review scores often are pointed to as the reason for failure to obtain funding. Indeed, over the past few years, peer review has come under increasing scrutiny. Critics have argued that peer review fails in its primary mission – to help funding agencies make the best decisions about which projects and which investigators to support. ….

Lab Size and Strategic Support of Science: Thoughts on Finding the Right Mix

November 6, 2015

Suppose a funding agency happens to have some extra money and needs to decide how to invest it. Should it invest that extra money in a large, highly productive laboratory, so that laboratory can expand a bit more? Or should it invest that extra money in a small to moderate size laboratory? Given our inability to predict the future with great certainty, which approach represents the smarter investment strategy? Jon Lorsch, the director of the National Institute for General Medical Sciences (NIGMS), has posted an interesting video on just this question. ….

Bolstering Trust in Science Through Rigorous Standards

October 30, 2015

Scientists have long considered the research process to be self-correcting; we trust that, even if scientists may sometimes make errors in the lab, those errors will eventually be discovered and corrected as others try to substantiate and extend original research findings. However, as stated in a commentary by NIH Director Francis Collins and NIH Deputy Director Larry Tabak, “A growing chorus of concern, from scientists and laypeople, contends that the complex system for ensuring the reproducibility of biomedical research is failing and is in need of restructuring.”
There are examples that indicate that our processes have room for improvement. For example, a 2008 study ….

Change is Coming: Updates to NIH Application Forms and Instructions

October 29, 2015

We periodically need to update our application forms and instructions to accommodate changing policy, new business needs, and sometimes (not often enough) to reduce the amount of information we ask of you. Given our constraints, we have been working to provide systems support to make the mechanics of these transitions easier for you. This particular set of changes implements a number of policy changes impacting applications submitted in 2016, which we announced in a series of recent NIH Guide notices. We would like to give you a quick overview of what is happening. ….

Proposed Changes to Human Subjects Regulations Are Open for Comment

October 23, 2015

As many in the research community know, the “Common Rule” refers to current regulations to protect individuals who participate in research as human subjects. The regulations, which have been in place since 1991, are followed by 18 federal agencies that support research – hence the name. Today I’d like to give you some background on how these regulations – and the conversation around these regulations – have evolved since 1991, and let you know about an opportunity to provide feedback on the modernization of these important rules. ….

Welcome to the Open Mike Blog at the NIH

October 19, 2015

Peter H. Schuck, the former deputy dean of the Yale Law School, recently published the book, Why Government Fails So Often: and How It Can Do Better, a rather depressing explanation of how public regard for government has steadily declined since the 60’s and 70’s. After 10 chapters that detail why the US Federal Government fails and fails again, along comes Chapter 11. No, not a chapter on bankruptcy, but on “Policy Successes.” And one of the several policy successes he mentions include an agency that you and I are well familiar with… the National Institutes of Health. The author notes, “Even small-government advocates generally concede an important role to the Federal Government [in] basic research – the creation of knowledge – in areas where private actors lack incentives to invest.” NIH-funded research has yielded important discoveries that have led to new treatments; has enabled excellent institutions of learning to flourish; has created cutting-edge job opportunities; and has forged strong collaborations with the private sector. ….