Perspectives on Peer Review at the NIH

November 12, 2015

In today’s New England Journal of Medicine, Richard Nakamura, the director of NIH’s Center for Scientific Review (CSR), and I published an essay titled “Reviewing Peer Review at the NIH.” As the competition for NIH research grants has become increasingly stiff, review scores often are pointed to as the reason for failure to obtain funding. Indeed, over the past few years, peer review has come under increasing scrutiny. Critics have argued that peer review fails in its primary mission – to help funding agencies make the best decisions about which projects and which investigators to support. ….

New Podcast on Certificates of Confidentiality

November 9, 2015

All About Grants is back with a new podcast episode on certificates of confidentiality (CoCs). Dr. Ann Hardy, NIH’s human subjects research protection officer, talks about how CoCs can enhance your human subjects research, as well as protect and benefit research participants …..

Lab Size and Strategic Support of Science: Thoughts on Finding the Right Mix

November 6, 2015

Suppose a funding agency happens to have some extra money and needs to decide how to invest it. Should it invest that extra money in a large, highly productive laboratory, so that laboratory can expand a bit more? Or should it invest that extra money in a small to moderate size laboratory? Given our inability to predict the future with great certainty, which approach represents the smarter investment strategy? Jon Lorsch, the director of the National Institute for General Medical Sciences (NIGMS), has posted an interesting video on just this question. ….

Bolstering Trust in Science Through Rigorous Standards

October 30, 2015

Scientists have long considered the research process to be self-correcting; we trust that, even if scientists may sometimes make errors in the lab, those errors will eventually be discovered and corrected as others try to substantiate and extend original research findings. However, as stated in a commentary by NIH Director Francis Collins and NIH Deputy Director Larry Tabak, “A growing chorus of concern, from scientists and laypeople, contends that the complex system for ensuring the reproducibility of biomedical research is failing and is in need of restructuring.”
There are examples that indicate that our processes have room for improvement. For example, a 2008 study ….

Change is Coming: Updates to NIH Application Forms and Instructions

October 29, 2015

We periodically need to update our application forms and instructions to accommodate changing policy, new business needs, and sometimes (not often enough) to reduce the amount of information we ask of you. Given our constraints, we have been working to provide systems support to make the mechanics of these transitions easier for you. This particular set of changes implements a number of policy changes impacting applications submitted in 2016, which we announced in a series of recent NIH Guide notices. We would like to give you a quick overview of what is happening. ….