In an effort to standardize terminology across the government, NIH is joining other federal agencies in using the term Notices of Funding Opportunities (NOFOs) rather than Funding Opportunity Announcement (FOA). You will see both terms in use while we work to update our websites and resources.
Many NOSIs designate parent announcements for application submission and most of our parent announcements were recently reissued with updated language and application forms (FORMS-F). So, checking the status of the designated FOA prior to submission is now more important than ever.
No, letters of intent are not required. Submission of a letter of intent is not binding and the letter is not part of the application review.