You may have noticed a growing trend at NIH to issue notices that highlight scientific areas of special interest. NIH Institutes and Centers have been increasingly using this approach as an alternative to issuing or reissuing program announcements. Instead, the notice indicates interest in a specific area, and points to the funding opportunity announcements applicants can use to apply. We are looking at ways to highlight these notices of special interest in the NIH Guide for Grants and Contracts. In the meantime, we encourage you to continue to track NIH notices as well as funding opportunity announcements.