NIH received over 20,000 applications for the Recovery Act-funded Challenge Grants program. This number roughly equals the total number of applications that NIH receives for any one of its three major review rounds each year and will require over 18,000 scientists to participate in the peer review process.

If you are conducting ongoing NIH-funded research involving previously approved uses of human stem cells, please know that your research may continue as NIH works to finalize the Guidelines for Human Stem Cell Research. While no new uses of human embryonic stem cells may be initiated in NIH-funded studies at this time, NIH will continue to accept competing applications proposing the use of human embryonic stem cells during the period of Guideline development.

NIH Acting Director Dr. Raynard Kington, M.D., Ph.D. has issued a statement condemning terrorist acts against researchers and institutions who use animals in their work. Dr. Kington emphasized the important role that these researchers play in the health of our nation and that federal funding supporting their work is based on national health needs. Dr. Kington further reiterated the high standards of accountability for animal welfare to which their research is held in order to receive federal funds.

Approximately 15,000 Challenge Grant applications are working their way through the submission process. Applications submitted by the initial April 27 deadline have until Friday, May 8 to complete the submission process.

The Academic Research Enhancement Award (AREA) grants support small research projects conducted by faculty and students at institutions that have not been major recipients of NIH research grant funds. This program has long sought to strengthen the research environment at such institutions by supporting the meritorious research of investigators who will then be able to involve students in the research process. Thanks to the American Recovery and Reinvestment Act of 2009, applicants to the AREA grants program may now request a maximum of $300,000 total direct costs plus applicable Facilities and Administrative (F&A)/ indirect costs for the entire project period of up to three years.

Over the years, there has been varying advice about the best type of grant with which to launch your career–R21, R03, R01? NIH recently issued a guide notice suggesting that you consider an R01 for a number of reasons. As you may know, New or Early Stage Investigator Status affords you special consideration during the peer review process for R01 grants.

BONUS!Check out these successful R01 applications from the National Institute of Allergies and Infectious Diseases.

Institutions must adhere to provisions of the PHS Policy, the Guide, and the commitments detailed in their Animal Welfare Assurance with OLAW. This includes advance planning for conditions that could arise as a result of a human pandemic (e.g., influenza) that could jeopardize the health and wellbeing of animals because of a lack of personnel to care for the animals and/or to conduct IACUC official business. Pandemic plans developed by institutions and IACUCs should include consideration of the following…

Finally, after the year-long study to assess NIH Peer Review, the first review meetings to use criterion scoring and the new 1 to 9 scoring scale are here! To help the extramural community prepare for these changes, we have created several sets of resources.

NIH will continue to receive applications through Grants.gov for all funding opportunities offered through the American Recovery and Reinvestment Act of 2009 (ARRA). Some concerns have been noted regarding the ability of Grants.gov to handle the additional demand for grant information and application submission related to ARRA. NIH is working closely with Grants.gov and other federal entities to take all possible steps to meet the needs of the biomedical research community. We will moniter the systems for issues and make adjustments as necessary.

Should you experience problems with Grants.gov that threaten the timely submission of your application, please take the following steps to document your difficulties.

New funding opportunities available through the American Recovery and Reinvestment Act of 2009 have been published and posted at http://grants.nih.gov/recovery. These include the NIH-wide initiative for research and research infrastructure support entitled the “Grand Opportunities,” a Biomedical Core Centers enhancement opportunity, and four initiatives through the National Institute of Mental Health (NIMH) for research on the heterogeneity of Autism Spectrum Disorders.