New “All About Grants” Podcast on Diversifying NIH’s Small Business Programs

In this next installment of the “All About Grants” podcast series, small business innovators can learn more about programs geared towards women-owned companies or those led by socially or economically disadvantaged groups.

Year in Reflection 2018

As we look back at 2018 – or for that matter any year – it seems reasonable to ask questions like “Irrespective of the outcomes, did we make the right decisions?” Given the choices we had, did we go about making our choices in a skillful way? And we can dig deeper – did we take steps to minimize uncertainty? … to mitigate the impact of bad outcomes? … to seek a diversity of opinions? … to make our decisions as data-driven as possible? …

The NCATS Trial Innovation Network – A Resource Supporting High Quality and Cost Effective Clinical Trials Available to You

Well-conducted randomized trials are considered the best method of providing evidence about the safety and efficacy of treatments to improve health. Each year, NIH Institutes and Centers spend an estimated $3-4 billion supporting clinical trial activities. These activities require high-level understanding of human biology, of manufacturing and pre-clinical research, and of regulatory requirements. The process of translating a new therapeutic from discovery to practice can be robust, but … at the same time is long and expensive – and despite the challenges inherent in complex, multi-disciplinary research sometimes too long and too expensive.

Two Years (or so) of “Open Mike”

Last year, as I reflected on finishing my first full year as NIH Deputy Director for Extramural Research, I noted five themes that reflected most of the content of this blog: applicant behavior, activity, and outcomes; peer review; basic science; biomedical research workforce and training; and scientific rigor, transparency, and research impact. Looking back on 2017, which was certainly a busy and active year, many of these themes continue to be at the forefront, though one in particular, the make-up and future of the biomedical research workforce, has been the center of much debate. ….

NIH’s Next Generation Researchers Policy Now Posted

Today we posted a policy (NIH Guide Notice NOT-OD-17-101) describing current plans for the Next Generation Researchers Initiative.  Since I first blogged about it in June, NIH leadership have reviewed data (see accompanying blog) and deliberated about how best to proceed.  Our goal is to increase the number of NIH-funded early-stage investigators and assure, as best we can, that funded early-stage investigators have a reasonable chance to secure stable funding during the earliest stages of their independent research careers. This new policy will supersede previous notices on new and early stage investigators (NOT-OD-08-012, NOT-OD-09-013 and NOT-OD-09-134). ….

Meet NIH & HHS in New Orleans for the NIH Regional Seminar, May 3-5!

Do you remember walking into the person’s office down the hall from you when you needed to ask a question, instead of “popping” them an email, instant message, or text? There’s no disputing that the digital age definitely has its advantages – making information sharing faster, cheaper, and more convenient, and allowing us to communicate locally and abroad in seconds. But in this fast paced world of instant communication – the internet, email, and all of our social media choices – sometimes we forget how valuable face-to-face interactions can be. That is exactly one of the reasons I love the NIH Regional Seminars on Grant Funding and Program Administration. The seminars give me the opportunity to join over 60 of my fellow NIH and HHS faculty in sharing our knowledge and perspectives to ….

Jazz Up Your Knowledge of NIH at the Spring 2017 NIH Regional Seminar in New Orleans

NIH will hold two NIH Regional Seminars on Program Funding and Grants Administration in 2017. This seminar is a great opportunity for investigators early in your career, research administrators and anyone new to working with the NIH grants process to connect with NIH and HHS staff in a central location. ….

The 21st Century Cures Act, and Perspectives from NIH

You may have been following news of the 21st Century Cures Act, a landmark piece of legislation with provisions for healthcare, medicine, and research. Republican and Democratic lawmakers supported this bill through its development and eventual passage, and yesterday, President Obama signed the bill into law. The Act establishes a multitude of important changes to our nation’s approach to supporting and funding health care, medical interventions, and research. Readers of this blog may be particularly interested in the many changes directly relevant to NIH’s mission. A New England Journal of Medicine Perspective essay ….

Build Mentor/Mentee Connections with MyNRMN

Are you a trainee looking for a mentor? Are you a scientist looking to foster careers in research? A new tool supported by NIH can help you build mentoring relationships and further the scientific enterprise through these connections. The National Research Mentoring Network (NRMN) is an NIH program developed in ….

How Many Researchers?

Last year, Kimble et al. published the findings of a workshop held at the University of Wisconsin on proposed strategies to rescue biomedical research in the US. The workshop organizers brought to together a number of stakeholders, who concluded that the research community faces two chief problems: “Too many researchers vying for too few dollars; too many postdocs competing for too few faculty positions.” These conclusions raises at least two questions: How many scientists, or more specifically how many principal investigators, does NIH fund? And how many scientists (more specifically aspiring principal investigators) want to receive NIH funding? Today I’d like to discuss two ways to examine these questions, by looking at the number of principal investigators awarded funding, not just on a yearly basis, but also in a way that captures a broader view of NIH-supported scientists over a window of time. ….