NIH has your back. We have a standing natural disaster policy that can protect you in the event a natural disaster such as a hurricane or blizzard closes your institution close to an application due date. Periodically we issue reminder notices, but even if we don’t issue a notice, the policy is still there to protect you from missing your deadline.
If your institution closes due to an emergency, keeping you from being able to get your application in on time, document the reason in the cover letter of your application. Keep in mind that the delay in the submission should not exceed the time period of your institution’s closure. Reasons for late applications are reviewed on a case-by-case basis, and no one at NIH can grant permission in advance for a late application.