NIH Director Francis Collins has approved more new human embryonic stem cell lines (hESCs) as eligible for use by NIH grantees in NIH-funded research. A total of 40 hESC lines now appear on the new NIH hESC Registry ; another 89 lines are currently pending review by the NIH. (See related December 2009 Nexus article .)
Some of the more recently approved lines include restrictions, which are limitations placed on the use of the hESC line by the provider of the line or by NIH. NIH clarified that grantees must honor all restrictions when using these lines, and will place a term on all hESC awards indicating that the grantee may only use those hESCs that appear on the Registry as eligible for NIH funding, and in accord with any restrictions placed on the use of those lines, in NIH Guide Notice NOT-OD-10-029 .