Hosted by Rutgers University, the PSI-Nature Structural Genomics Knowledgebase (PSI-SGKB) serves as a continually updated gateway to research data and other resources from the Protein Structure Initiative (PSI). First established in spring 2008, the PSI-SGKB is now re-launched in collaboration with Nature Publishing Group (NPG), with NPG contributing editorial content to help researchers stay informed about developments in structural biology and structural genomics.
Protein structure can tell us a great deal about how living systems function and can help with drug development and in understanding human disease. However, protein structure information is sometimes not easily interpretable by researchers working outside structural biology.
“One of the overarching goals of the PSI is to enable scientists interested in a particular protein family to obtain a relevant structure that can guide functional or disease-related studies,” said Jeremy M. Berg, Ph.D., director of the National Institute of General Medical Sciences, the component of the National Institutes of Health (NIH) that developed the PSI. “The PSI-SGKB is a portal to the wealth of resources available for speeding discoveries about these molecules so vital to our health.”
The PSI was launched in 2000 by NIH to determine protein structures on a large scale. Over the course of the initiative, PSI-supported research centers have produced more than 3,200 structures, published around 1,000 scientific papers, and developed many techniques now employed in labs around the world.
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